Efficient Chimeric Mouse Production Using a Novel Embryonic Stem Cell LIne
Researchers need an embryonic stem cell line that is able to participate in the formation of chimeric animals even after prolonged cultivation in vitro. A novel DGES1 embryonic stem cell line was demonstrated to efficiently produce transgenic mouse using the B6D2F1 blastocysts and CD-1 recipients. Mice were housed in Optimice cages. Keywords: Transgenic, Genetics, Gene Expression, Embryology, embryonic stell cell line, C57BL/6J, DBA/2JRccHsd, CD-1, Optimice, mice, mouse
G. V. Kontsevaya, N. A. Feofanova, A. G. MenzorovI, E. Pristyazhnyuk, A. V. Smirnov, N. R. Battulin, L. A. Gerlinskaya. Efficient chimeric mouse production using a novel embryonic stem cell line. Russian Journal of Genetics: Applied Research, December 2017, Volume 7, Issue 8, pp 806–810; https://link.springer.com/article/10.1134/S2079059717050100
