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Biodecontamination of an IVC Rack Using Automated, Integrated HHP Decontamination
This study shows the comprehensive 6-log biodecontamination of an IVC rack within a decontamination chamber using automated, integrated HHP technology, resulting in a repeatable, validatable kill .throughout the animal rack and cages. To ensure animal welfare and optimal experiment outcomes, animal housing systems are designed with contamination control, food and water delivery, and ease of…
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Investigation Of A Novel Thermal Support System To Recover Post‑Anesthetized Mice
Laboratory rodents are typically housed in rooms set at temperatures between 20-22°C, primarily to match the comfort requirements of the humans working in these rooms. These temperatures are well below the rodent thermoneutral zone of 30-32°C, temperatures at which rodents maintain their body temperature without expending extra energy to keep warm. Housing rodents in temperatures…
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Ammonia Levels in Animal Care Systems Cages in Higher Humidity Conditions
Animal Care System’s revolutionary approach to individual cage ventilation employs a unique one-pass low-velocity linear air technology which eliminates the introduction of air turbulence and high air velocity, while ensuring maximum cage air quality at a low airflow. Cage ammonia and other environmental parameters were measured in all three Animal Care Systems rack types (Optimice,…
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Acceleration Associated with Rotatation of Animal Care Systems Carousel Racks
This study was undertaken to approximate the acceleration that a rodent would experience during routine rotation of the rack by personnel, and to compare this motion to those laboratory rodents may undergo routinely in day to day activities. Keywords: Welfare, Housing Effects,Behavior, rotational force, rotation, acceleration, density, high density, Optimice, mice, mouse Citation: Chua, B.…
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Flexible Solutions Addressing Operational Needs are Key to Success in Vivarium Planning
The design team specified Animal Care Systems ultra high density Optimice Caging system because it made efficient use of the available floor space. Keywords: Vivarium Planning,Design, Efficiency, density, high density, ultra high density, Optimice, design, layout, architect, mice, mouse Citation: Haugh, K. Flexible Solutions Addressing Operational Needs are Key to Success in Vivarium Planning. CRB…
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M.I.C.E. and Optimice Cage Rack Validation for ABSL-3
Tracer gases and smoke are used to verify cage integrity for ABSL-3. Keywords: Biocontainment, CL3, ABSL-3, Bioexclusion, cross-contamination, Optimcice, M.I.C.E, mice, mouse Citation: Rivard, G. M.I.C.E. and Optimice Cage Rack Validation for ABSL-3. MouseCare Inc., Ithaca, NY (2007)
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Effect of Caging System on an MHV-Model of Experimental Infection
Three caging systems were compared: Static Microisolators (SMI), Ventilated Microisolators (VMI) and Microenvironmental comfort Isolation Containment Enrichment cages (M.I.C.E.®) to determine if the caging system influences the symptomatology of experimentally infected mice. The secondary objective was to evaluate the efficacy of these caging systems to contain the infection. Keywords: Biocontainment, Bioexclusion, cross-contamination, M.I.C.E, mice, mouse…
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Biocontainment Study in Optimice IVC Rack by IDEXX Bioresearch
For 12 weeks, the Optimice rack was populated with cages of infected and uninfected mice (referred to as ‘colony’ mice) to emulate a rack with low to moderate disease prevalence. Keywords: Biocontainment, Bioexclusion, cross-contamination, Optimice, mice, mouse Citation: Biocontainment Study in Optimice IVC Rack. IDEXX BioResearch, Columbia, Missouri. (2017)
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Applicability of the Optimice Cage System in a Toxicology Animal Facility
The OptiMICE® rack system provides an easier rotation schedule, reduces odor in the room, and occupies half of the space than the See-Through III system. Using a divider in the cage doubles cage density. As technicians become more familiarized with the new rack system, they become more efficient in dosing. Standard dosing time for oral…
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Survey of NH3 Production in Optimice and Double-Size M.I.C.E. Cages
A review of various strains breeding performance in MICE and Optimice cross referenced to ammonia production. Keywords: Microenvironment, Cage environment, Ammonia, NH3, waste gas, air flow, air quality, breeding, repoduction, Optimice, M.I.C.E, mouse, mice, Citation: Survey of NH3 Production in OptiMICE (OM) and double-size M.I.C.E. cages (2007)