Biodecontamination of an IVC Rack Using Automated, Integrated HHP Decontamination

This study shows the comprehensive 6-log biodecontamination of an IVC rack within a decontamination chamber using automated, integrated HHP technology, resulting in a repeatable, validatable kill .throughout the animal rack and cages. To ensure animal welfare and optimal experiment outcomes, animal housing systems are designed with contamination control, food and water delivery, and ease of use in mind. For example, Individually ventilated cages (IVCs) mounted onto a containment rack with a center plenum design to draw air through the IVCs and out of the rack system. IVCs use low-velocity airflow and filtration, which helps prevent cross-contamination between cages by minimizing the spread of airborne particles. Further the single-directional airflow improves air quality by lowering humidity and removing waste gases, such as carbon dioxide and ammonia.

Citation: Grinstead, S., Apolinar, R. Biodecontamination of an IVC Rack Using Automated, Integrated HHP Decontamination. Curis Decontamination (2023)