What is the Best Airflow and Airflow Patterns in an Individually Ventilated Cage?
Category: Blog
THE FIRST INDIVIDUALLY VENTILATED CAGING SYSTEMS (IVC) were brought onto the laboratory animal market about 40 years ago. Those systems…
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Optimice Cage Top Prop
Category: Training Videos
Need more space in your Biosafety Cabinet during cage change? Watch how the innovative and ergonomic rodent cage top prop…
Read More A Rac/Cdc42 Exchange Factor Complex Promotes Formation of Lateral Filopodia and Blood Vessel Lumen Morphogenesis
Category: Published Studies
This paper shows that lumen formation requires early cytoskeletal remodelling and lateral cell–cell contacts, mediated through the RAC1 guanine nucleotide…
Read More Actin Disruption Results in Altered Morphology of Basal Tubulobulbar Complexes in Rat Seminiferous Epithelium
Category: Published Studies
These results are consistent with the conclusion that intact networks of actin filaments are required for maintaining the structural integrity…
Read More High Resolution Localization of Rab5, EEA1, and Nectin-3 to Tubulobulbar Complexes in the Rat Testis
Category: Published Studies
This paper concludes that at tubulobulbar complexes in Sertoli cells of the seminiferous epithelium, the identity of ‘bulbs’ as putative…
Read More Reproductive Effects of Tumor Necrosis Factor (TNF) Gene Knockout in Mice
Category: Published Studies
This data should be taken into account when prescribing long-term anti-TNF therapy to patients of reproductive age. Mice were housed…
Read More R-Loops in Proliferating Cells but Not in the Brain: Implications for AOA2 and Other Autosomal Recessive Ataxias
Category: Published Studies
R-loops constitute a novel trigger for genomic instability and the accumulation of these structures may represent an underlying and contributing…
Read More Effect of Chronic Inhalation of Silicon Dioxide Nanoparticles (Tarkosil 25) On the Expression of Key Genes of the Serotonergic System in the Mouse Brain
Category: Published Studies
The chronic inhalation of silicon dioxide nanoparticles does not activate nonspecific immunity in the brain, but it exerts contrasting genotype-specific…
Read More Unexpected Phenotypic Effects of a Transgene Integration Causing a Knockout of the Endogenous Contactin-5 Gene in Mice
Category: Published Studies
This paper reports a novel Cntn5 knockout mouse line generated by a random transgene integration as an outcome of pronuclear…
Read More Morphophysiological Effects of Insertional Mutagenesis of the Contactin 5 (Cntn5) Gene in Transgenic Mice
Category: Published Studies
The morphophysiological effects of integrating the transgenic construction providing the production of the human granulocyte–macrophage colony-stimulating factor in the milk…
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