-
Illuminance Levels Comparison in Optimice and Other Cages. National Jewish Health
One can safely assume that Optimice caging situated in a room illuminated to industry recommendations. Keywords: Room environment, Light levels, lux, illumination, Optimice mice, mouse would expose its animals to light levels far below the 325-lux upper limit indicated in “Guide for Care and Use of Laboratory Animals, 8th Ed.” Citation: Illuminance Levels Comparison in…
-
A Third Party Perspective: Retrospective Analysis of Reproductive Performance in Animal Care Systems Optimice® Ventilated Racks
This study summarizes this vivarium’s retrospective data and compares reproductive performance in theircolonies to commercial vendor statistics. Keywords: Breeding, Reproduction, Optimice, mice Citation: Rose, N. A Third Party Perspective: Retrospective Analysis of Reproductive Performance in Animal Care Systems Optimice® Ventilated Racks. Contact ACS for corresponding author information. (2019)
-
Reducing Exposure to Laboratory Animal Allergens
Ambient allergen concentrations were measured when mice were maintained under several conditions: conventional housing versus ventilated cage racks operated under negative or positive pressure. We found that housing mice in ventilated cages operated under negative pressure reduced ambient mouse allergen (Mus m 1) concentrations tenfold. Animal Care Systems is the original direct-exhaust negative pressure IVC…
-
The Effects of Cage Design on Airborne Allergens and Endotoxin in Animal Rooms: High-Volume Measurements with an Ion-Charging Device
The use of filter tops on cages corresponds to a 50-fold reduction in mean levels of both airborne allergens (P < 0.001) and endotoxin (P < 0.001). The use of vented cages with filtered exhaust ports was associated with additional reductions. Animal Care Systems is the original direct-exhaust negative pressure IVC System with a filtered…
-
Assessing the Risk of Transmission of Three Infectious Agents Among Mice Housed in a Negatively Pressurized Caging System
This paper concludes the caging systems run at negative pressure effectively reduce personnel exposure to allergens and may also inhibit the transmission of infectious diseases. Animal Care Systems is the original direct-exhaust negative pressure IVC System. Keywords: Room Ventilation, allergens, Laboratory Animal Allergy, ACH, air changes per hour; cfm, cubic feet per minute; air quality,…
-
Particulate Matter in Animal Rooms Housing Mice in Microisolation Caging
This paper concludes that considering the heat load, odor, and overall particulate concentration in the room, placing individually ventilated caging under negative pressure with exhaust air returned to the HVAC system appears to be the optimal overall choice when using microisolation housing for rodents. Animal Care Systems is the original direct-exhaust negative pressure IVC System.…
-
Influence of 5 Different Caging Types and the Use of Cage-Changing Stations on Mouse Allergen Exposure
Allergen concentrations were lowest in rooms with sealed IVC under positive or negative pressure, with unsealed IVC under negative pressure, and with static microisolation caging. Animal Care Systems is the original direct-exhaust negative pressure IVC System. Keywords: Room Ventilation, allergens, Laboratory Animal Allergy, ACH, air changes per hour; cfm, cubic feet per minute; air quality,…
-
Effect of Room Ventilation Rates in Rodent Rooms with Direct-Exhaust IVC Systems
When IVC are directly exhausted from a rodent housing room, the air quality of the room can become independent of the intracage air quality and may reduce the need for high room ventilation rates. Air quality in the room and in the cages were acceptable with room ventilation rates of 5 to 6 ACH in…
-
Ammonia Levels in Animal Care Systems Cages
Cage ammonia and other environmental parameters were measured in all three Animal Care Systems rack types (Optimice®, Optirat® Plus and Optirat® GenII) at standard recommended airflow rates, to determine values for routine monitoring of cage ammonia between cage changes over time. Keyword: Ammonia, NH3, waste gas, air flow, air quality Citation: Chua, B. Ammonia Levels…
-
Ammonia Levels and Reproductive Performance of CD1(ICR) Mice in an Optimice® Rack Using Two Different Styles of Cage Filters
An evaluation of breeding performance, cage airflow and ammonia levels in flat filter Optimice cages to ensure they were comparable to those in the original pleated filter cages. Keywords: breeding, reproduction, pleated filter, flat filter, air flow, air quality, Optimice, mice Citation: Ruggeri C. Ammonia Levels and Reproductive Performance of CD1(ICR) Mice in an Optimice®…