Unexpected Phenotypic Effects of a Transgene Integration Causing a Knockout of the Endogenous Contactin-5 Gene in Mice
This paper reports a novel Cntn5 knockout mouse line generated by a random transgene integration as an outcome of pronuclear microinjection. Mice were housed in Optimice cages. Keywords: Metabolism, Transgenic, Gene Expression, insertional mutagenesis, Cntn5 deficiency, obesity, hypertension, C57BL/6 J, Optimice, Mouse, mice
Alexander V. Smirnov, Galina V. Kontsevaya, Natalia A. Feofanova, Margarita V. Anisimova, Irina A. Serova, Lyudmila A. Gerlinskaya, Nariman R. Battulin, Mikhail P. Moshkin, Oleg L. Serov. Unexpected phenotypic effects of a transgene integration causing a knockout of the endogenous Contactin-5 gene in mice. Transgenic Res, February 2018, Volume 27, Issue 1, pp 1–13 (2017); https://link.springer.com/article/10.1007/s11248-017-0053-y
