Graft-Infiltrating PD-L1hi Cross-Dressed Dendritic Cells Regulate Antidonor T Cell Responses in Mouse Liver Transplant Tolerance “
The findings suggest that graft-infiltrating PD-L1hi CD-DCs may play a key role in the regulation of alloimmunity and in the induction of liver transplant tolerance.Mice were housed in Optimice cages. Keywords: Transgenic, Gene Expression, transplant rejection, liver transplant, organ transplant, C57BL/6, B6SJL-PtprcaPepcb/BoyJ, B6.Cg-Tg(Itgax-Venus)1Mnz/J, C3H/HeJ, Optimice, mouse, mice
Ono, Y., Perez-Gutierrez, A., Nakao, T., Dai, H., Camirand, G., Yoshida, O., Yokota, S., Stolz, D. B., Ross, M. A., Morelli, A. E., Geller, D. A. and Thomson, A. W. Graft-infiltrating PD-L1hi cross-dressed dendritic cells regulate anti-donor T cell responses in mouse liver transplant tolerance. Hepatology. Accepted Author Manuscript. http://onlinelibrary.wiley.com/doi/10.1002/hep.29529/full