Morphophysiological Effects of Insertional Mutagenesis of the Contactin 5 (Cntn5) Gene in Transgenic Mice
The morphophysiological effects of integrating the transgenic construction providing the production of the human granulocyte–macrophage colony-stimulating factor in the milk of the mouse line (GM9) (the insertion of the construction in the intron of the contactin 5 (Cntn5) gene) isdescribed. Mice were housed in Optimice cages. Keywords: Metabolism, Transgenic, Gene Expression, insertional mutagenesis, fat metabolism, C57BL/6, Optimice, Mouse, mice
A. V. Smirnov, N. A. Feofanova, G. V. Kontsevaya, M. V. Anisimova, I. I. Kovrigin, I. A. Serova, M. P. Moshkin, L. A. Gerlinskaya, N. R. Battulin. Morphophysiological effects of insertional mutagenesis of the contactin 5 (Cntn5) gene in transgenic mice. Russian Journal of Genetics: Applied Research, December 2017, Volume 7, Issue 8, pp 799–805; https://link.springer.com/article/10.1134/S2079059717050185
