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Ammonia Levels in Animal Care Systems Cages
Cage ammonia and other environmental parameters were measured in all three Animal Care Systems rack types (Optimice®, Optirat® Plus and Optirat® GenII) at standard recommended airflow rates, to determine values for routine monitoring of cage ammonia between cage changes over time. Keyword: Ammonia, NH3, waste gas, air flow, air quality Citation: Chua, B. Ammonia Levels…
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Ammonia Levels and Reproductive Performance of CD1(ICR) Mice in an Optimice® Rack Using Two Different Styles of Cage Filters
An evaluation of breeding performance, cage airflow and ammonia levels in flat filter Optimice cages to ensure they were comparable to those in the original pleated filter cages. Keywords: breeding, reproduction, pleated filter, flat filter, air flow, air quality, Optimice, mice Citation: Ruggeri C. Ammonia Levels and Reproductive Performance of CD1(ICR) Mice in an Optimice®…
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Let it Flow: A Closer Look at the Quality and Sterility of Standard NSG Mouse Drinking Water
The purpose of this study was to evaluate the quality and sterility of acidified water and acidified autoclaved water over time when given to NSG mice in our facility. We hypothesized there would be no differences in the pH and/or microbial growth over time between the two water types. Keywords: water quality, NSG, Optimice, mice,…
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Analysis of Paired Breeder Performance in an Animal Care Systems Optimice® Ventilated Rack After Transfer from Both Open-Top Cages and a Motorized Ventilated Rack
A comparison of breeding performance in this low-flow ventilated carousel rack to our motorized ventilated library-style rack and open-top cages. Keywords: breeding, reproduction, IVC, Optimice, mice Citation: Gorman C. Analysis of Paired Breeder Performance in an Animal Care Systems Optimice® Ventilated Rack After Transfer from Both Open-Top Cages and a Motorized Ventilated Rack. Poster presented…
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Evaluation of Exhaust Air Dust PCR Testing of the Bedding Sentinel Cage Filter
The evaluation of a filter sampling method compared to test results with results obtained using traditional methods for soiled bedding sentinels. Keywords: sentinels, health monitoring, EAD, PCR testing, filter, Optimice, mice Citation: Monts de Oca, N. Evaluation of Exhaust Air Dust PCR Testing of the Bedding Sentinel Cage Filter.
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Blower-Free IVC System Technology
https://youtu.be/KpYYdBqHmeA Ever wonder about the revolutionary Animal Care Systems IVC rack system technology? Watch this video to learn what sets us apart from other IVC system setups. Keywords: IVC Rack System, airflow, Exhaust Ventilated Caging
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IVC Rack Status Monitor
To ensure continuous and adequate airflow to your IVC rack system for rats and mice, watch this instructional video on unpacking, setup, calibration and usage of the rack status monitor. Keywords: Measure airflow, measure air changes/hour, ACH,
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IVC Rack Anemometer
Need to spot check airflow to your IVC rack system? Here’s how you can use the ACS rack anemometer to ensure ideal airflow. Keywords: Measure airflow, measure air changes/hour, ACH,
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Effect of Chronic Inhalation of Silicon Dioxide Nanoparticles (Tarkosil 25) On the Expression of Key Genes of the Serotonergic System in the Mouse Brain
The chronic inhalation of silicon dioxide nanoparticles does not activate nonspecific immunity in the brain, but it exerts contrasting genotype-specific effects on the expression of the 5-HT1A receptor in the hippocampus. Mice were housed in Optimice cages. Keywords: Silicon dioxide nanoparticles, specific pathogen-free mice, SPF, Tarkosil nanoaerosol, 5-HT1A receptor, environmental toxicity, Balb/c, C57Bl/6, Optimice, mouse,…
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Unexpected Phenotypic Effects of a Transgene Integration Causing a Knockout of the Endogenous Contactin-5 Gene in Mice
This paper reports a novel Cntn5 knockout mouse line generated by a random transgene integration as an outcome of pronuclear microinjection. Mice were housed in Optimice cages. Keywords: Metabolism, Transgenic, Gene Expression, insertional mutagenesis, Cntn5 deficiency, obesity, hypertension, C57BL/6 J, Optimice, Mouse, mice Alexander V. Smirnov, Galina V. Kontsevaya, Natalia A. Feofanova, Margarita V. Anisimova,…