The Effects of Cage Design on Airborne Allergens and Endotoxin in Animal Rooms: High-Volume Measurements with an Ion-Charging Device

The use of filter tops on cages corresponds to a 50-fold reduction in mean levels of both airborne allergens (P < 0.001) and endotoxin (P < 0.001). The use of vented cages with filtered exhaust ports was associated with additional reductions. Animal Care Systems is the original direct-exhaust negative pressure IVC System with a filtered exhaust port. Keywords: Room Ventilation, allergens, Laboratory Animal Allergy, ACH, air changes per hour; cfm, cubic feet per minute; air quality, negative exhaust, direct exhaust ventilation, EVC, filtered exhaust port

Platts-Mills, James A.; Custis, Natalie J.; Kenney, Alice; Tsay, Amy; Chapman, Martin D.; Feldman, Sanford H.; Platts-Mills, Thomas A. E. The Effects of Cage Design on Airborne Allergens and Endotoxin in Animal Rooms: High-Volume Measurements with an Ion-Charging Device. Journal of the American Association for Laboratory Animal Science, Volume 44, Number 2, March 2005, pp. 12-16(5). http://www.ingentaconnect.com/contentone/aalas/jaalas/2005/00000044/00000002/art00002