Addition of Interleukin-6 to Mouse Embryo Culture Increases Blastocyst Cell Number and Influences the Inner Cell Mass to Trophectoderm Ratio
These data show that IL-6 improved mouse embryo development when cultured individually in complex media; however, an excess of IL-6 may be detrimental. Mice were housed in Optimice cages. Keywords: Transgenic, Genetics, Cell culture, Culture media, Cytokines, Embryology, Fertilization in vitro, Preimplantation, Optimice, mice, mouse
Rebecca L Kelley and David K Gardner. Addition of interleukin-6 to mouse embryo culture increases blastocyst cell number and influences the inner cell mass to trophectoderm ratio. Clin Exp Reprod Med. 2017 Sep; 44(3): 119-125; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636923/