Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses
A class of environmental compounds derived from dietary, microbial, and industrial sources that induce CD1d-dependent intestinal inflammation is identified, that are potentially associated with Intestinal Bowel Disease. Colitis experiments, were performed in Optimice cages under sterile conditions. Keywords: Microbiome, Gut Microbiota, Inflammatory Bowel Disease, Colitis, Transgenic, Gene Expression, Optimice, Mice, Mouse
Shankar S. Iyer, Thomas Gensollen, Amit Gandhi, Sungwhan F. Oh, Joana F.Neves, Frederic Collin, Richard Lavin, Carme Serra, Jonathan Glickman, Punyanganie S.A. de Silva, R. Balfour Sartor, Gurdyal Besra, Russell Hauser, Anthony Maxwell, Amadeu Llebaria, Richard S. Blumberg. Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses. Cell, Volume 173, Issue 5, 17 May 2018, Pages 1123-1134.e11 https://www.sciencedirect.com/science/article/pii/S0092867418305683
