Food Deprivation Increases Hepatic Hepcidin Expression and Can Overcome the Effect of Hfe Deletion in Male Mice
These results indicate that Hamp1 induction by food deprivation is independent of HFE and suggest that targeting the pathway regulated by food deprivation could have clinical benefit in iron loading conditions. Mice were housed in Optimice cages. Keywords: Nutrition, Nutrional deficiencies, Transgenic, Gene Expression, food deprivation, hereditary hemochromatosis, Optimice, mouse, mice
Cornel S. G. Mirciov, Sarah J. Wilkins, Gregory J. Anderson, and David M. Frazer. Food deprivation increases hepatic hepcidin expression and can overcome the effect of Hfe deletion in male mice. The FASEB Journal, 25 May 2018; https://www.fasebj.org/doi/abs/10.1096/fj.201701497RR
